Mas del Botó is located in the Cortiella Valley, in the term of Alforja, Baix Camp region, although geographically, geologically and landscape-wise it is considered part of the Priorat. It is one of the three areas included in the scope of the UNESCO Intangible Heritage of Humanity bid for Priorat that lie outside of Priorat county.

From a winemaking point of view, Mas del Botó historically belongs to the D.O. Tarragona.

Hydrologically it is within the Ebro Basin. The headwaters of the Cortiella river, which gives its name to the Valley, are found on this estate. It is a tributary of the Siurana river.